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SARS coronavirus X4 like protein domain : ウィキペディア英語版
SARS coronavirus X4 like protein domain

In molecular biology, SARS coronavirus X4 like protein domain is commonly shortened to SARS-X4. This protein domain is only found in viruses. It causes SARS Severe acute respiratory syndrome in humans which causes high rates of death and mortality. It is produced by a type of virus named the coronavirus (SARS-CoV). X4 is the protein domain which is a unique type I transmembrane protein.
==Function==
The precise protein of SARS X4 like protein remains to be elucidated however it has been suggested that it has binding activity to integrin I domains. Additionally it is thought to induce apoptosis via a caspase dependent
pathway in different types of tissue; or in simpler terms, inducing cell death through an enzymatic pathway. Also, it contains a motif which has been demonstrated to mediate COPII dependent transport out of the endoplasmic reticulum, and the protein is targeted to the Golgi apparatus. It remains unknown as to why the protein may be involved with cell trafficking.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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